Immunoglobulin heavy variable (IgHV) gene mutation and micro-RNA expression in Burkitt’s lymphoma at Moi Teaching and Referral Hospital in Western Kenya
; (2019)
xmlui.dri2xhtml.METS-1.0.item-type
ArticleBurkitt’s lymphoma (BL) is a virus associated childhood B-cell cancer common in Eastern Africa. Continued survival of B-cells in germinal centres depend on expression of high affinity immunoglobulins (Ig) to complementary antigens by somatic hypermutation of Ig genes. Cellular microRNAs, non-coding RNAs have been reported to play role in cell cycle regulation. Both viral antigen dependent mutation and micro-RNA expression maybe involved in BL pathogenesis.
Mpiga chapa
African Health Sciences
- Journal Articles [57]
Preview
- Jina:
- Ndede Isaac_et al 2019-1-.pdf
Files in this item
The following license files are associated with this item: