Growth Inhibitory Effect of Datura stramonium and Tamarindus indica on Resistant Malaria Mosquito Body Surface and Gut Microbiota

Abstract

Bacteria mediated resistance which possibly is initiated when the vectors pick insecticides through feeding, inhalation or contact of their cuticle is threatening effective malaria vector control. This study tested growth inhibitory effectiveness of crude Datura stramonium leaf and seed extracts, it’s seed isolate F7, Tamarindus indica fruit pulp extracts on bacteria isolated from midgut and cuticle of Anopheles gambiae resistant to deltamethrin. Data was analyzed by R version 4.2.3. Seed extracts isolate F7’ had superior growth inhibition efficacy comparable to only lincomycin on gramnegative bacteria of genus Elizabethkingia, Aeromonas, Pseudomonas, Klebsiella, Proteus, Serratia, Shigella, Acinetobacter, salmonella Enterobacter, and Citrobacter, bacteria isolated from the mosquito. F7 can be considered for control of microbiota induced deltamethrin resistance.